• Taurina 600mg - 100 cápsulas - Nootrópicos Perú
  • Taurina 600mg - 100 cápsulas Nootrópicos Perú
  • Taurina 600mg - 100 cápsulas Nootrópicos Perú
1 3

Nootrópicos Perú

Taurine 600mg - 100 capsules

Taurine 600mg - 100 capsules

S/. 100.00 PEN
S/. 100.00 PEN
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Taurine is a non-essential amino acid found in high concentrations in the heart, brain, retina and blood platelets. Although it is not technically an amino acid in the traditional sense (due to the absence of a carboxyl), it plays a vital role in several metabolic functions. It is often found in energy drinks, supplements, and foods, such as meat and fish.

Why is it considered a nootropic? It is considered a nootropic due to its ability to improve cognitive function, protect the brain, and improve mood. Its influence on neurotransmitters and neuronal health makes it a popular supplement for those looking to optimize brain function.

Mechanism of action: Taurine acts as an inhibitory neurotransmitter modulating the GABA system in the brain. It also has antioxidant properties, protects cells from oxidative damage, and helps regulate calcium balance in cells, which is vital for neurotransmission and the overall health of neurons.

Benefits:

  1. Neuroprotection:
    • Reducing Oxidative Stress: Taurine has antioxidant properties that can help combat oxidative stress in the brain. Oxidative stress is a known cause of cellular damage and is implicated in a number of neurodegenerative diseases.
    • Prevention of Neuroinflammation: Taurine may help reduce inflammation in the brain, which may contribute to the prevention of diseases such as Alzheimer's and Parkinson's.
  2. Improved Cognitive Function:
    • Memory Enhancement: Taurine may increase neurogenesis, especially in the hippocampus, a brain region associated with memory.
    • Improved Learning: Some animal studies have shown that taurine can improve learning ability.
  3. Mood Stabilization:
    • Anxiety Reduction: By acting on the GABAergic system, taurine can have anxiolytic effects, reducing feelings of anxiety and stress.
    • Antidepressant Effect: Antidepressant properties have been observed in animal studies, although more research is required in humans.
  4. Cardiovascular health:
    • Blood Pressure Regulation: Taurine can help dilate blood vessels, which can reduce blood pressure.
    • Cholesterol Reduction: Taurine has been shown to reduce LDL cholesterol levels and increase HDL, which is beneficial for cardiovascular health.
  5. Visual Support:
    • Retinal Protection: Taurine is essential for the proper functioning of photoreceptor cells in the retina, and its deficiency can lead to vision problems.
  6. Regulation of Metabolism:
    • Diabetes Support: Taurine has been shown to improve insulin sensitivity and may help regulate blood glucose levels.
  7. Reduction of Muscle Fatigue:
    • Improved Endurance: By helping to eliminate waste products such as ammonia, it can delay fatigue and improve endurance during exercise.
  8. Liver Health:
    • Liver Protection: Taurine may protect the liver from damage induced by toxins such as alcohol and certain medications.
    • Prevention of Hepatic Steatosis: Taurine can help reduce fat accumulation in the liver, preventing conditions such as non-alcoholic fatty liver.
  9. Immune System Health:
    • Stimulation of Defenses: Taurine can enhance the function of certain immune cells, thus strengthening the immune system and helping to fight infections.
  10. Bone Health: Promoting Bone Density: Taurine may play a role in bone formation, contributing to greater bone density and preventing diseases such as osteoporosis.
These benefits are based on a combination of scientific research, animal studies, and anecdotal evidence. It is essential that consumers are aware that while some benefits are well established, others may require more research to be definitively confirmed. Additionally, it is always advisable to consult a health professional before starting any supplementation.

Absorption: Taurine is easily absorbed from the gastrointestinal tract and is primarily metabolized in the liver. Ingestion with food can facilitate its absorption.

Adverse effects and contraindications:

  • Adverse effects: These are rare, but may include nausea, headache, and dizziness at very high doses.
  • Contraindications: People with kidney problems should avoid taurine or consult a doctor before taking it. It is also advisable for pregnant or breastfeeding women to consult with a health professional before consuming taurine. As always, it is important not to exceed the recommended doses and it is advisable to start with a low dose to evaluate individual tolerance.

More information about Taurine and its dosage: https://nootropicsexpert.com/taurine/

References on studies:

[Yo] Curran CP, Marczinski CA “Taurine, caffeine, and energy drinks: Reviewing the risks to the adolescent brain.” Birth Defects Research 2017 Dec 1;109(20):1640-1648. ( source )

[ii] Wu JY, Prentice H. “Role of taurine in the central nervous system” Journal of Biomedical Science 2010; 17(Suppl 1): S1. ( source )

[iii] Leon R., Wu H., Jin Y., Wei J., Buddhala C., Prentice H., Wu JY “Protective function of taurine in glutamate-induced apoptosis in cultured neurons.” Journal of Neuroscience Research . 2009 Apr; 87(5):1185-94. ( source )

[iv] Schaffer S., Kim HW “Effects and Mechanisms of Taurine as a Therapeutic Agent” Biomolecules & Therapeutics (Seoul). 2018 May; 26(3): 225–241. ( source )

[v] Gebara E., Udry F., Sultan S., Toni N. “Taurine increases hippocampal neurogenesis in aging mice.” Stem Cell Research . 2015 May;14(3):369-79. ( source )

[saw] Stipanuk MH “Metabolism of sulfur-containing amino acids.” Annual Review of Nutrition 1986;6:179-209. ( source )

[vii] Laidlaw SA, Shultz TD, Cecchino JT, Kopple JD “Plasma and urine taurine levels in vegans.” American Journal of Clinical Nutrition . 1988 Apr;47(4):660-3. ( source )

[viii] El Idrissi A., Boukarrou L., Splavnyk K., Zavyalova E., Meehan EF, L'Amoreaux W. “Functional implication of taurine in aging.” Advances in Experimental Medicine and Biology . 2009;643:199-206. ( source )

[ix] Eppler B., Dawson R. “The Effects of Aging on Taurine Content and Biosynthesis in Different Strains of Rats” in Schaffer S., Lombardini JB, Huxtable RJ (eds) Taurine 3. Advances in Experimental Medicine and Biology , vol 442. Springer, Boston, MA ( source )

[x] Andrews S., Schmidt CL “TITRATION CURVES OF TAURINE AND OF CYSTEIC ACID” Journal of Biological Chemistry 1927 73: 651-. ( source )

[xi] Yamori Y., Liu L., Mori M., Sagara M., Murakami S., Nara Y., Mizushima S. “Taurine as the nutritional factor for the longevity of the Japanese revealed by a world-wide epidemiological survey.” Advances in Experimental Medicine and Biology . 2009;643:13-25 ( source )

[xii] Wu GF, Ren S. Tang RY, Xu C., Zhou JQ, Lin SM, Feng Y., Yang QH, Hu JM, Yang JC “Antidepressant effect of taurine in chronic unpredictable mild stress-induced depressive rats” Scientific Reports . 2017; 7: 4989. ( source )

[xiii] Toyoda A., Iio W. “Antidepressant-like effect of chronic taurine administration and its hippocampal signal transduction in rats.” Advances in Experimental Medicine and Biology 2013;775:29-43 ( source )

[xiv] O'Donnell CP, Allott KA, Murphy BP, Yuen HP, Proffitt TM, Papas A., Moral J., Pham T., O'Regan MK, Phassouliotis C., Simpson R., McGorry PD “Adjunctive Taurine in First- Episode Psychosis: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study.” Journal of Clinical Psychiatry . 2016 Dec; 77(12):e1610-e1617. ( source )

[xv] Pereira C., et. to the. “Mitochondrial Agents for Bipolar Disorder” International Journal of Neuropsychopharmacology 2018 Jun 1; 21(6): 550–569. ( source )

[xvi] Suarez LM, Munoz MD, Martin Del Rio R., Solis JM “Taurine content in different brain structures during aging: effect on hippocampal synaptic plasticity.” Amino Acids 2016 May;48(5):1199-208 ( source )

[xvii] Akande MG, Aliu YO, Ambali SF, Ayo JO “Taurine mitigates cognitive impairment induced by chronic co-exposure of male Wistar rats to chlorpyrifos and lead acetate.” Environmental Toxicology and Pharmacology . 2014;37(1):315-25. ( source )

[xviii] Kumari N., Prentice H., Wu JY “Taurine and its neuroprotective role.” Advances in Experimental Medicine and Biology . 2013;775:19-27 ( source )

[xix] El Idrissi A., Shen CH, L'amoreaux WJ “Neuroprotective role of taurine during aging.” Amino Acids . 2013 Oct;45(4):735-50. ( source )

[xx] Ward RJ, Dexter DT, Crichton RR “Ageing, neuroinflammation and neurodegeneration.” Frontiers in Bioscience . 2015 Jun 1;7:189-204. ( source )

[xxi] Sun Q., Hu H., Wang W., Jon H., Feng G., Jia N. “Taurine attenuates amyloid beta 1-42-induced mitochondrial dysfunction by activation of SIRT1 in SK-N-SH cells.” Biochemical and Biophysical Research Communications . 2014;447(3):485-9. ( source )

[xxii] Pasantes-Morales H., Ramos-Mandujano G., Hernandez-Benitez R. “Taurine enhances proliferation and promotes neuronal specification of murine and human neural stem/progenitor cells.” Advances in Experimental Medicine and Biology 2015;803:457-72 ( source )

[xxiii] Yamori Y. “Food factors for atherosclerosis prevention: Asian perspective derived from analyzes of worldwide dietary biomarkers.” Experimental & Clinical Cardiology . 2006 Summer;11(2):94-8. ( source )

[xxiv] Hernández-Benítez R., Vangipuram SD, Ramos-Mandujano G., Lyman WD, Pasantes-Morales H. “Taurine enhances the growth of neural precursors derived from fetal human brain and promotes neuronal specification.” Developmental Neuroscience. 2013;35(1):40-9. ( source )

[xxv] Suarez LM, Bustamante J., Orensanz LM, Rio M., Solis JM “Cooperation of taurine uptake and dopamine D1 receptor activation facilitates the induction of protein synthesis-dependent late LTP.” Neuropharmacology . 2014;79:101-11. ( source )

[xxvi] Ghanizadeh A., Akhondzadeh S., Hormozi M., Makarem A., Abotorabi-Zarchi M., Firoozabadi A. “Glutathione-related factors and oxidative stress in autism, a review.” Current Medicinal Chemistry . 2012;19(23):4000-5. ( source )

[xxvii] Park E., Cohen I., Gonzalez M., Castellano MR, Flory M., Jenkins EC, Brown WT, Schuller-Levis G. “Is Taurine a Biomarker in Autistic Spectrum Disorder?” Advances in Experimental Medicine and Biology . 2017;975 Pt 1:3-16 ( source )

[xxviii] Chen VC, Chiu CC, Chen LJ, Hsu TC, Tzang BS “Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats.” Behavioral Brain Research . 2018 Aug 1;348:219-226 ( source )

[xxix] Chen VC, Hsu TC, Chen LJ, Chou HC, Weng JC, Tzang BS “Effects of taurine on resting-state fMRI activity in spontaneously hypertensive rats” PLOS 1 12(12): e0190203. (source )

[xxx] Arnold PD, Sicard R., Burroughs E. “Glutamate Transporter Gene SLC1A1 Associated With Obsessive-compulsive Disorder” Archives of Genetic Psychiatry . 2006;63(7):769-776. ( source )

[xxxi] Jia F., Yue M., Chandra D., Keramidas A., Goldstein PA, Homanics GE, Harrison NL “Taurine Is a Potent Activator of Extrasynaptic GABA A “Receptors in the Thalamus” The Journal of Neuroscience 2 January 2008, 28 (1) 106-115 ( source )

[xxxii] Schaffer S., Kim HW “Effects and Mechanisms of Taurine as a Therapeutic Agent” Biomolecules and Therapeutics (Seoul) . 2018 May; 26(3): 225–241. ( source )

[xxxiii] Shao A., Hathcock JN “Risk assessment for the amino acids taurine, L-glutamine and L-arginine.” Regulatory Toxicology and Pharmacology . 2008 Apr;50(3):376-99 ( source )

[xxxiv] Sved DW, Godsey JL, Ledyard SL, Mahoney AP, Stetson PL, Ho S., Myers NR, Resnis P., Renwick AG “Absorption, tissue distribution, metabolism and elimination of taurine given orally to rats.” Amino Acids 2007;32(4):459-66. ( source )

[xxxv] Ghandforoush-Sattari M., Mashayekhi S., Krishna CV, Thompson JP, Routledge PA “Pharmacokinetics of oral taurine in healthy volunteers.” Journal of Amino Acids 2010;2010:346237. ( source )

[xxxvi] Zhang L., Yuan Y., Tong Q., Jiang S., Xu Q., Ding J., Zhang L1, Zhang R., Zhang K. “Reduced plasma taurine level in Parkinson's disease: association with motor severity and levodopa treatment .” International Journal of Neuroscience . 2016;126(7):630-6 ( source )

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