L-Theanine 200mg - 100 capsules

L-Theanine is an amino acid found mainly in the leaves of green tea (Camellia sinensis) and in some mushrooms. It is known for its relaxing properties without causing drowsiness, and is often taken in combination with caffeine to enhance concentration and mental focus.

Why is it considered a nootropic? It is considered a nootropic due to its ability to improve various cognitive functions, such as attention, concentration, and memory, without causing significant side effects. Additionally, it has the power to improve mood and reduce anxiety, contributing to better brain function in general.

Mechanism of action: L-Theanine acts on several fronts within the central nervous system:

• It increases levels of inhibitory neurotransmitters such as GABA, which has a calming effect.
• Reduces excitatory levels such as glutamate.
• Increases the production of alpha brain waves, associated with a state of alert relaxation.
• It can influence dopamine and serotonin, neurotransmitters linked to mood and satisfaction.

Detailed benefits of L-Theanine:

1. Deep Relaxation without Drowsiness : One of the most notable benefits of L-Theanine is its ability to induce a feeling of calm without producing drowsiness. This relaxation can help relieve daily stress, nervousness and worries, allowing users to face challenges and stressful situations with a clearer and more balanced mind.
2. Synergy with Caffeine : When combined with caffeine, L-Theanine can improve concentration, precision and speed of attention. This is especially beneficial for activities that require a high degree of focus and precision. Additionally, it reduces the unwanted side effects of caffeine, such as jitters or fast heartbeat.
3. Reduction of Anxiety Symptoms : L-Theanine's ability to increase levels of GABA and serotonin in the brain may help reduce the perception of stress and anxiety, facilitating a calmer and more serene state of mind in situations that would normally be stressful. .
4. Improved Sleep Quality : Although it does not directly induce drowsiness, L-Theanine may improve sleep quality by allowing a smoother transition to sleep and increasing the duration of deep sleep. This can result in a more refreshed wake-up call and increased energy throughout the day.
5. Brain Protection : L-Theanine has antioxidant properties that can protect neurons from oxidative damage. Additionally, it may help prevent age-related cognitive decline and improve synaptic plasticity, essential for learning and memory.
6. Enhancement of Memory and Learning : Studies have indicated that L-Theanine can improve memory and learning ability, probably due to its effect on neurotransmission and neuronal protection.
7. Elevated Mood : By influencing the release of neurotransmitters such as dopamine and serotonin, L-Theanine can improve mood, relieve symptoms of mild depression, and promote an overall sense of well-being.
8. Improved Immune Function : Some research suggests that L-Theanine may enhance immune system function, increasing resistance to certain infections.
9. Blood Pressure Reduction : In individuals prone to hypertension, L-Theanine can help reduce blood pressure, contributing to cardiovascular health.

Absorption : L-Theanine is easily absorbed by the intestine and can cross the blood-brain barrier, reaching the brain in approximately 30 minutes after ingestion. It is best absorbed on an empty stomach, although it can also be taken with food.

Adverse effects and contraindications : L-Theanine is generally considered safe and is well tolerated by most people. However, some people may experience mild side effects such as headache, dizziness, or digestive problems. It is not recommended for people with hypotension (low blood pressure) as it may lower blood pressure further. As always, it is advisable to consult a health professional before starting any supplement, especially if you are taking medication or have any pre-existing medical conditions.

More information about L-Theanine and its dosage: https://nootropicsexpert.com/l-theanine/

References on studies:

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[ii] Yamada T., Terashima T., Wada K., Ueda S., Ito M., Okubo T., Juneja LR, Yokogoshi H. “Theanine, r-glutamylethylamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation.” Life Sciences . 2007 Sep 29;81(16):1247-55. ( source )

[iii] Song CH, Jung JH, Oh JS, Kim KS “Effects of Theanine on the Release of Brain Alpha Wave in Adult Males.” Korean Journal of Nutrition 2003 Nov;36(9):918-923. ( source )

[iv] Hajira SG et. Et. “Developing Brain Vital Signs: Initial Framework for Monitoring Brain Function Changes Over Time.” Frontiers in Neuroscience . 2016 May 12;10:211 ( source )

[v] Nathan PJ, Lu K., Gray M., Oliver C. “The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent.” Journal of Herbal Pharmacotherapy . 2006;6(2):21-30. ( source )

[vi] Lu M., Gray, Oliver C. “The Neuropharmacology of L-Theanine(N-Ethyl-L-Glutamine)” Journal of Herbal Pharmacotherapy Volume 6, Issue 2, 2006 ( source )

[vii] Kimura K., Ozeki M., Juneja LR, Ohira H. “L-Theanine reduces psychological and physiological stress responses.” Biological Psychology . 2007 Jan;74(1):39-45. ( source )

[viii] Kakuda T., Nozawa A., Unno T., Okamura N., Okai O. “Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat.” Biosci Biotechnol Biochem . 2000 Feb;64(2):287-93. ( source )

[ix] Yokogoshi H., Kobayashi M., Mochizuki M., Terashima T. “Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats.” Neurochemistry Research . 1998 May;23(5):667-73. ( source )

[x] Kobayashi K., Nagato Y., Nobuyuki, Sugimoto S. “Effects of L-Theanine on the Release of .ALPHA.-Brain Waves in Human Volunteers.” Nippon Nogeikagaku Kaishi 72(2):153-157 · December 1997 ( source )

[xi] US Patent Application 20040171624; Japanese Patent Application 2001-253740 ( source )

[xii] Chen Z., Li Y., Zhao LC, Zhou BF, Yang J., Wang ZW, Guo M., Wu YF “[A study on the association between tea consumption and stroke]. -in Chinese Zhonghua Liu Xing Bing Xue Za Zhi . 2004 Aug;25(8):666-70. ( source )

[xiii] Park SK, Jung IC, Lee WK, Lee YS, Park HK, Go HJ, Kim K., Lim NK, Hong JT, Ly SY, Rho SS “A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study.” Journal of Medicinal Food . 2011 Apr;14(4):334-43. ( source )

[xiv] Garcia R. “Stress, hippocampal plasticity, and spatial learning.” Synapse . 2001 Jun 1;40(3):180-3. ( source )

[xv] Joëls M., Karst H., DeRijk R., de Kloet ER “The coming out of the brain mineralocorticoid receptor.” Trends in Neuroscience . 2008 Jan;31(1):1-7. ( source )

[xvi] Tamano H., Fukura K., Suzuki M., Sakamoto K., Yokogoshi H., Takeda A. “Preventive effect of theanine intake on stress-induced impairments of hippocamapal long-term potentiation and recognition memory.” Brain Research Bulletin . 2013 Jun;95:1-6. ( source )

[xvii] “L-Theanine Supplement Review” Cleveland Clinic Wellness clevelandclinicwellness.com Retrieved June 3, 2016 ( source )

[xviii] Owen GN, Parnell H., De Bruin EA, Rycroft JA “The combined effects of L-theanine and caffeine on cognitive performance and mood.” Nutritional Neuroscience . 2008 Aug;11(4):193-8. ( source )

[xix] Vuong QV, Stathopoulos CE, Golding JB, Nguyen MH, Roach PD “Optimum conditions for the water extraction of L-theanine from green tea.” Journal of Separation Science . 2011 Sep;34(18):2468-74. ( source )